2024 ARCHIVES
Tuesday, March 26
Registration and Morning Coffee7:00 am
Chairperson's Remarks
Kevin Davies, PhD, Executive Editor, The CRISPR Journal; Author, Editing Humanity: The CRISPR Revolution and the New Era of Genome Editing
Damian Verdnik, PhD, Director, Diagnostics, Dx PMO, Invetech
FIRESIDE CHAT: Convergence of Artificial Intelligence and Precision Oncology
Douglas Flora, MD, Executive Medical Director, Oncology Services, St. Elizabeth Healthcare; Editor-in-Chief, AI in Precision Oncology Journal
Artificial Intelligence (AI) is exhibiting immense power to transform the practice of science and medicine, from genome analysis and drug discovery to health data and the practice of medicine. Nowhere is this more evident than in the field of oncology. In 2019, clinical oncologist Douglas Flora read Deep Medicine, the best-selling book by Scripps Research President Eric Topol. He was immediately convinced of the power of AI to transform the work of his medical staff—and the lives of his patients. Last year, Dr. Flora launched a new journal, AI in Precision Oncology, to disseminate stories and examples of the transformative potential of AI in oncology. In this fireside chat, Dr. Flora will share his AI epiphany and offer real-world examples of how AI is already changing the practice of medicine—at his organization (St. Elizabeth Healthcare) and beyond.
AI and Genomics Come Together
Artificial intelligence (AI) promises to enable the analysis of trillions of genomic, molecular, clinical, and epidemiological data points, offering unprecedented insights into health and disease, the development of drugs and diagnostics, and empowering precision medicine. Our distinguished panel will review the opportunities, challenges, and innovations in applying emerging AI tools to biological data, and their potential to revolutionize drug development, diagnostics, and precision medicine.
Kari Stefansson, MD, PhD, CEO, deCODE genetics
Atul Butte, MD, PhD, Distinguished Professor and Institute Director, University of California
Pankaj Vats, PhD, Senior Bioinformatics/Genomics Scientist, NVIDIA
Jonathan M. Carlson, PhD, Managing Director, Microsoft Health Futures
Refreshment Break9:30 am
Geoff McCleary, Vice President, Global Connected Health, Capgemini
Precisely Practicing Medicine from 700 Trillion Points of Data
There is an urgent need to take what we have learned in our new data-driven era of medicine, and use it to create a new system of precision medicine, delivering the best, safest, cost-effective preventative or therapeutic intervention at the right time, for the right patients. Dr. Butte's teams at the University of California build and apply tools that convert trillions of points of molecular, clinical, and epidemiological data into diagnostics, therapeutics, and new insights into disease.
Artificial Intelligence in Therapeutic Discovery, Development, and Delivery: From Multimodal Analysis to Individualized Treatments
Sean Khozin, MD, MPH, CEO, CEO Roundtable on Cancer and Project Data Sphere | Founder, Phyusion | Research Affiliate, MIT
AI is catalyzing rational drug discovery and design using multimodal data and playing a pivotal role in optimizing Phase 1 trial designs. AI-powered approaches are also reshaping clinical development programs through methods such as covariate adjustments and complex biomarkers. The intersection of AI at the point-of-care underscores its capacity to enable personalized treatments via data-driven insights delivered as clinical decision support tools.
Harnessing Human Genetics with AI
Enjoy Lunch on Your Own11:20 am
Session Break12:55 pm
Chris M. Hartshorn, PhD, Chief, Digital & Mobile Technologies Section—CTSA Program, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH)
Challenges to Precision X (Health, Medicine, Oncology, Nutrition, etc.): The Need for AI/ML to Become Transformational & the NIH Approach
A recent topic of much discussion has been the use of AI/ML for healthcare application; its use for biomedical research is not novel, though its clinical use has increased substantially of late—and simultaneously, understanding of its current limitations. The talk will focus on the challenges of bringing AI/ML to its 'big data' analytical endpoint for the totality of medical evidence, and the NIH funding landscape aiming to address these.
Integration of AI-Accelerated Solutions in Healthcare to Transform Precision Medicine
AI-driven platforms are significantly advancing the field of precision medicine, enabling rapid genetic diagnosis, accelerating genomic analysis, and leading the way in drug discovery. Case studies highlight the transformative impact of these technologies such as Nanopore genome sequencing for rapid genetic diagnosis in critical care; GPU-Accelerated analysis of population-scale genomic datasets, and generative AI for small-molecule drug discovery. By leveraging AI, these advancements are improving patient outcomes and driving innovation in medical research and drug development.
Unlocking the Future: Implementing Precision Medicine with the Power of AI
Partha Das, MD, Global Medical Director, Precision Medicine & Pipeline, Janssen Oncology
The presentation will explore the transformative potential of AI in healthcare. It begins by defining precision medicine and highlighting its promises, including improved outcomes and cost savings. The challenges in implementing precision medicine are discussed, leading to the introduction of AI as a solution. The presentation showcases AI applications across genomics, drug development, diagnostics, and more, with case studies demonstrating its impact. Ethical considerations and collaboration opportunities are addressed, and future trends are explored. The presentation concludes by emphasizing AI's role in revolutionizing precision medicine.
Robert Cook, PhD, Senior Vice President, Research & Development, Castle Biosciences
Spatialomics provides a rich data set to interrogate multiple pathways of disease in parallel. Using Artificial Intelligence to interpret these pathways has the potential to unlock new understanding with profound abilities to improve patient management. This talk will explore how this synergy of AI and spatialomics has been used and validated in Barrett’s esophagus to predict a patient’s future risk of progression to esophageal adenocarcinoma.
Session Break3:00 pm
Grand Opening Refreshment Break in the Exhibit Hall with Poster Viewing3:15 pm
Mara G. Aspinall, Partner, Illumina Ventures; Professor of Practice, Arizona State University; Editor, Sensitive & Specific: The Testing Newsletter
Artificial Intelligence Innovation for Precision Medicine
Eric Topol, MD, Founder and Director, Scripps Research Translational Institute; Executive Vice President and Professor, Scripps Research
A visionary at the intersection of medicine and technology, Dr. Eric Topol articulates the big picture for radical improvement in healthcare through personalized and data-driven medicine. Eric published three books, over 1,200 peer reviewed publications, and provides his reasoned perspective on medical AI frequently on social media. We will discuss his views on the current state of precision medicine and artificial intelligence, including generative AI in medicine, diagnostics, and clinical trials.
AI in Precision Medicine: Innovation and Growth Opportunities
The convergence of artificial intelligence (AI) and precision medicine promises to revolutionize health care. Generative AI, machine learning, and sophisticated computational power promise to enable clinical decision support and diagnostics, support drug development, and optimize personalized medicine.
Michael Pellini, MD, General Partner, S32
Charity Williams, Partner, Cooley LLP
Reception in the Exhibit Hall with Poster Viewing (Sponsorship Opportunity Available)5:30 pm
Close of Day6:30 pm
Wednesday, March 27
Registration and Morning Coffee7:30 am
Edward Abrahams, PhD, President, Personalized Medicine Coalition
Paul Beresford, Vice President and General Manager, CDx, Agilent Technologies
The State of Innovation in Diagnostic Testing for Personalized Medicine
Integrating diagnostics into clinical care faces numerous challenges, including regulatory, reimbursement, and clinical adoption among others, before the promise of personalized medicine can be realized. This panel, with support from the Personalized Medicine Coalition, will consider these barriers and propose solutions to overcome them.
Peter Bach, MD, CMO, Delfi Diagnostics
Christopher Conn, PhD, Global Director, Clinical Biomarkers & Diagnostics, Diagnostics Strategy Lead, Amgen
Jeffrey Venstrom, MD, CMO, GRAIL
Justin Odegaard, MD, PhD, Vice President, Clinical Development, Guardant Health
Transition to Sessions9:00 am
AI in Medicine—Is the Promise Real?
Dr. Flora will delve into the fascinating world of Artificial Intelligence (AI) in Medicine. The speaker will open with an engaging discussion on the promise of AI in transforming healthcare. Attendees will gain valuable insights into the current applications and future possibilities of AI in the medical field. The talk will serve as a primer for clinicians, industry experts, and researchers who are eager to understand whether the hype surrounding AI in Medicine is justified or merely an illusion. The speaker will provide real-world examples and success stories, showcasing how AI can revolutionize diagnostics, treatment plans, and patient care. By attending this talk, participants will leave with a deeper understanding of the transformative power of AI in Medicine and its potential to improve healthcare outcomes.
Informed, Data-Driven Patient Care in Oncology
Ezra Cohen, MD, CMO, Oncology, Tempus Labs, Inc.
A decade ago, somatic genome sequencing disrupted oncologic management paradigms by informing personalization of therapy. Presently, the combination of multiomic, pathologic, radiographic, and clinical data is further revolutionizing oncology by shifting from personalized to truly individualized care. This lecture will discuss some technologies being developed to improve treatment decisions and patient outcomes.
Coffee Break in the Exhibit Hall with Poster Viewing10:40 am
The Rise of Phenomics
Scott Penberthy, PhD, Managing Director, Applied AI, Google Cloud
Phenomics is a new, AI-driven approach to oncology and health care pioneered by Dr. Leroy Hood, a pioneer of genomics, next-generation sequencing, and the human genome project. We'll discuss how phenomics combines data from nanoscale, next-generation sequencing reads to the daily steps on a Fitbit to diagnose, debug, and repair our bodies in often dramatic ways—today.
Navigating the AI Revolution in Precision Oncology
Sanjay Juneja, MD, Hematologist & Medical Oncologist, Mary Bird Perkins Cancer Center
The discovered value of precision and molecular therapy, both on a tumor level as well as that relating to germline polymorphisms, has made the research and discovery of clinically relevant biomarkers explode. In a field already starved for physicians to fulfill our country's unmet cancer needs, how can AI immediately alleviate the growing concerns of health inequity as it relates to democratizing optimal care?
Enjoy Lunch on Your Own1:00 pm
Refreshment Break in the Exhibit Hall with Poster Viewing (Sponsorship Opportunity Available)1:30 pm
Close of Artificial Intelligence in Precision Medicine Conference2:00 pm
Conference Programs